Premium
In vivo cartilage contact deformation of human ankle joints under full body weight
Author(s) -
Wan Lu,
de Asla Richard J.,
Rubash Harry E.,
Li Guoan
Publication year - 2008
Publication title -
journal of orthopaedic research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.041
H-Index - 155
eISSN - 1554-527X
pISSN - 0736-0266
DOI - 10.1002/jor.20593
Subject(s) - cartilage , ankle , osteoarthritis , joint (building) , deformation (meteorology) , weight bearing , in vivo , materials science , strain (injury) , biomedical engineering , articular cartilage , anatomy , medicine , composite material , structural engineering , surgery , pathology , alternative medicine , microbiology and biotechnology , biology , engineering
Quantitative data on in vivo deformation of articular cartilage is important for understanding the articular joint function and the etiology of degenerative joint diseases such as osteoarthritis. This study experimentally determined the in vivo cartilage thickness distribution and articular cartilage contact strain distribution in human ankle joints under full body weight loading conditions using a combined dual fluoroscopic and magnetic resonance imaging technique. The average cartilage thickness with the joint non–weight bearing was found to be 1.43 mm ± 0.15 mm and 1.42 mm ± 0.18 mm in the distal tibial and proximal talar cartilage layers, respectively. During weight bearing on a single leg, the strain distribution data revealed that 42.4% ± 15.7% of the contact area had contact strain higher than 15% in the ankle joint. Peak cartilage contact strain reached 34.5% ± 7.3%. This quantitative data on in vivo human cartilage morphology and deformation demonstrated that the cartilage may undergo large deformations under the loading conditions experienced in human ankle joints during daily activities. The in vivo cartilage contact deformation can be used as displacement boundary conditions in three‐dimensional (3D) finite element models of the joint to calculate in vivo 3D articular cartilage contact stress/strain distributions. © 2008 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 26:1081–1089, 2008