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Nanobiomaterial applications in orthopedics
Author(s) -
Christenson Elizabeth M.,
Anseth Kristi S.,
van den Beucken Jeroen J.J.P.,
Chan Casey K.,
Ercan Batur,
Jansen John A.,
Laurencin Cato T.,
Li WanJu,
Murugan Ramalingam,
Nair Lakshmi S.,
Ramakrishna Seeram,
Tuan Rocky S.,
Webster Thomas J.,
Mikos Antonios G.
Publication year - 2007
Publication title -
journal of orthopaedic research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.041
H-Index - 155
eISSN - 1554-527X
pISSN - 0736-0266
DOI - 10.1002/jor.20305
Subject(s) - nanobiotechnology , orthopedic surgery , nanotechnology , biomedical engineering , engineering , medicine , materials science , surgery , nanoparticle
Advancements in nanobiotechnology are revolutionizing our capability to understand biological intricacies and resolve biological and medical problems by developing subtle biomimetic techniques. Nanocomposites and nanostructured materials are believed to play a pivotal role in orthopedic research since bone itself is a typical example of a nanocomposite. This article reviews current strategies using nanobiomaterials to improve current orthopedic materials and examines their applications in bone tissue engineering. Preliminary investigations support the potential of nanobiomaterials in orthopedic applications; however, significant advancements are necessary to achieve clinical use. Overall, current trends in nanobiotechnology foreshadow a bright future through the use of nanobiomaterials in the orthopedic domain. © 2006 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 25:11–22, 2007