Premium
Nerve endings of the wrist joint: A preliminary report of the dorsal radiocarpal ligament
Author(s) -
Lin YuTe,
Berger Richard A.,
Berger Evelyn J.,
Tomita Kazunari,
Jew Jean Y.,
Yang Chao,
An KaiNan
Publication year - 2006
Publication title -
journal of orthopaedic research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.041
H-Index - 155
eISSN - 1554-527X
pISSN - 0736-0266
DOI - 10.1002/jor.20166
Subject(s) - anatomy , free nerve ending , ligament , cadaver , wrist , population , posterior interosseous nerve , articular capsule of the knee joint , joint capsule , medicine , pathology , knee joint , surgery , alternative medicine , environmental health , palsy
As part of an investigation of the articular nerve ending populations in the wrist joint capsule associated with the anterior and posterior interosseous nerves, this study addresses the nerve ending population in the dorsal radiocarpal ligament. The ligaments were harvested from four wrists of two fresh cadavers within 12 h of death. Tissues were fixed, cryostat sectioned, and processed for fluorescence immunohistochemistry using antibody to protein gene product 9.5 (PGP 9.5), a general or pan neuronal marker, and a secondary antibody conjugated to a fluorescent tag (Alexa Fluor 488). The sections were evaluated with a confocal laser microscope and an image analyzer. Labeled nerve endings were mapped, measured, and categorized. Type I (Ruffini‐like ending), Type III (Golgi‐like tendon organ) and Type IV (noncorpuscular) nerve endings could be identified in all four DRC ligaments, with Types I and IV dominating. These receptors were distributed primarily over the superficial two thirds of the ligament (>80%), and near the bony attachments (>70%). The dorsal radiocarpal ligament has a rich sensory innervation from the posterior interosseous nerve terminating in nerve endings located in the superficial two‐thirds of the ligaments, primarily near bony attachment sites. © 2006 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 24:1225–1230, 2006