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Visualization by magnetic resonance imaging of focal cartilage lesions in the excised mini‐pig knee
Author(s) -
Koh H. L.,
Kshirsagar A.,
Herrod N. J.,
Carpenter T. A.,
Hall L. D.,
Hunziker E. B.,
Tyler J. A.
Publication year - 1996
Publication title -
journal of orthopaedic research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.041
H-Index - 155
eISSN - 1554-527X
pISSN - 0736-0266
DOI - 10.1002/jor.1100140409
Subject(s) - magnetic resonance imaging , cartilage , materials science , nuclear magnetic resonance , articular cartilage , knee joint , femur , joint (building) , biomedical engineering , anatomy , chemistry , osteoarthritis , physics , radiology , medicine , pathology , alternative medicine , surgery , engineering , architectural engineering
This study showed that magnetic resonance imaging can be used to visualize partial thickness cartilage lesions, 0.7 × 10 mm in area and 0.5 mm in depth, surgically induced in the femur (femoropatellar compartment) of a mini‐pig knee joint. Formalin‐fixed joints, intact as well as disarticulated, were studied by high resolution imaging using a 2.35 T, 31 cm horizontal‐bore superconducting magnet. The two‐dimensional and three‐dimensional spatial resolutions achievable were as follows: 0.12 × 0.23 mm (two‐dimensional) and 0.35 × 0.35 × 0.35 mm (three‐dimensional) for the intact joint, and 0.08 × 0.08 mm (two‐dimensional) and 0.14 × 0.14 × 0.27 mm (three‐dimensional) for the disarticulated joint. These results demonstrate that magnetic resonance imaging, together with edge detection and volume rendering, can be used to visualize focal cartilage lesions.