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Bone response to hydroxyapatite‐coated and commercially pure titanium implants in the human arthritic knee
Author(s) -
Carlsson L.,
Regnér L.,
Johansson C.,
Gottlander M.,
Herberts P.
Publication year - 1994
Publication title -
journal of orthopaedic research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.041
H-Index - 155
eISSN - 1554-527X
pISSN - 0736-0266
DOI - 10.1002/jor.1100120218
Subject(s) - apposition , titanium , implant , dentistry , materials science , osseointegration , biomedical engineering , bone formation , radiography , medicine , anatomy , surgery , metallurgy , endocrinology
Rough and smooth commercially pure (c.p.) titanium implants and hydroxy‐apatite‐coated (HA‐C) implants were inserted in arthritic human knees and left in situ in order to compare the response of bone to these three implants. Radiographic examination alone could not determine if bone apposition had occurred. After 3 and 6 months, histomorphometric analyses of undecalcified sections, 10 μm thick, revealed a statistical significance in the amount of bone apposition to rough‐surfaced and HA‐C implants as compared with smooth uncoated implants. Most of the rough‐surfaced c.p. titanium implants and the HA‐C implants had achieved bone apposition on the order of 50%. No statistically significant differences in apposition were seen between the rough‐surfaced and HA‐C implants. The smooth c.p. titanium implants were mostly encapsulated in fibrous tissue.