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Biomplant surfaces: Binding of fibronectin and fibroblast adhesion
Author(s) -
Cannas Mario,
Denicolai Fernando,
Webb Lawrence X.,
Gristina Anthony G.
Publication year - 1988
Publication title -
journal of orthopaedic research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.041
H-Index - 155
eISSN - 1554-527X
pISSN - 0736-0266
DOI - 10.1002/jor.1100060108
Subject(s) - fibronectin , titanium , adhesion , adhesive , fibroblast , baby hamster kidney cell , cell adhesion , materials science , chemistry , cell , composite material , biochemistry , metallurgy , layer (electronics) , in vitro
The adhesion of baby hamster kidney 21C/13 fibroblasts to surfaces of passivated titanium, carbon fibers, bioactive glasses B5 and B6, fibronectin‐precoated passivated titanium, and fibronectin‐precoated B6 was quantified. The order of adhesive cell avidity for the uncoated surfaces was passivated titanium (greatest), B6 and carbon fibers (intermediate), and B5 (least). Precoating with fibronectin enhanced the adhesive characteristics of fibroblasts on passivated titanium and B6 by 74% and 118%, respectively.