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Age‐related changes in bone in the dog: Fluid spaces and their potassium content
Author(s) -
Pinto Manuel R.,
Kelly Patrick J.
Publication year - 1984
Publication title -
journal of orthopaedic research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.041
H-Index - 155
eISSN - 1554-527X
pISSN - 0736-0266
DOI - 10.1002/jor.1100020102
Subject(s) - extracellular fluid , osteocyte , chemistry , potassium , body water , interstitial fluid , zoology , cortical bone , extracellular , medicine , age groups , water content , endocrinology , anatomy , biology , geology , biochemistry , body weight , osteoblast , in vitro , geotechnical engineering , demography , organic chemistry , sociology
We measured erythrocyte, plasma, osteocyte, extravascular extracellular, and total water fluid spaces and calculated their K content in cortical bone of dogs of various age. Total and exchangeable K were measured by atomic absorption spectroscopy and by volume of distribution techniques, respectively. All fluid spaces in bone decreased with increasing age of the dogs. The total and exchangeable K contents of cortical bone and the K content calculated from the fluid spaces were within the same range in each age group. These values all fell with increasing age.