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Effects of freezing and freeze‐drying on the biomechanical properties of rat bone
Author(s) -
Pelker Richard R.,
Friedlaender Gary E.,
Markham Thomas C.,
Panjabi Manohar M.,
Moen Clinton J.
Publication year - 1983
Publication title -
journal of orthopaedic research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.041
H-Index - 155
eISSN - 1554-527X
pISSN - 0736-0266
DOI - 10.1002/jor.1100010409
Subject(s) - torsion (gastropod) , freeze drying , compression (physics) , materials science , reduction (mathematics) , biomedical engineering , anatomy , composite material , chemistry , medicine , mathematics , chromatography , geometry
The effects of various preservation techniques on the biomechanical properties of bone have been investigated in a rat model. Freezing of the specimens to −20°C, −70°C, and −196°C did not adversely affect the strength of long bones tested in torsion or of vertebral bodies tested in compression. Freeze‐drying did not markedly affect the compression properties of the vertebral specimens; however, it did produce a significant deleterious reduction in the torsional strength of the long bones.