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Potassium leakage from Escherichia coli cells treated by organic ammonium salts
Author(s) -
Mlynarčík Dušan,
Sirotková Libuša,
Devínsky Ferdinand,
Masárová Ľubomíra,
Pikulíková Aurélia,
Lacko Ivan
Publication year - 1992
Publication title -
journal of basic microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.58
H-Index - 54
eISSN - 1521-4028
pISSN - 0233-111X
DOI - 10.1002/jobm.3620320113
Subject(s) - potassium , escherichia coli , inhibitory postsynaptic potential , ammonium , leakage (economics) , antimicrobial , chemistry , membrane , minimum inhibitory concentration , potassium channel , membrane potential , nuclear chemistry , inorganic chemistry , biochemistry , biophysics , biology , organic chemistry , gene , macroeconomics , neuroscience , economics
The effect of the homologous series of 1,1‐dialkylpiperidinium bromides on the potassium leakage from Escherichia coli cells has been studied. The minimum concentration for each compound which is able to release maximum of cellular potassium has been determined and correlated with the inhibitory activities of the compounds. The relationship between the structure and the activity enables to consider the K + leakage as the marker of inhibitory activity of the membrane active antimicrobials.