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Isolation and characterization of an alkaloid‐blocked mutant of Claviceps paspali
Author(s) -
Pertot Elizabeta,
GabercPorekar Vladimira,
Sočič Helena
Publication year - 1990
Publication title -
journal of basic microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.58
H-Index - 54
eISSN - 1521-4028
pISSN - 0233-111X
DOI - 10.1002/jobm.3620300115
Subject(s) - lysergic acid , ergometrine , mutant , alkaloid , mycelium , ergonovine , chemistry , strain (injury) , isolation (microbiology) , biology , stereochemistry , biochemistry , microbiology and biotechnology , botany , anatomy , psychology , psychiatry , myocardial infarction , pharmacology , gene , angina
Abstract After UV‐irradiation an alkaloid‐blocked mutant of Claviceps paspali was isolated from an ergometrine and lysergic acid amides (1:1) producing strain. The formation of ergometrine is blocked in this particular mutant strain which accumulates only lysergic acid amides. A significant morphological differentation of colonies of mutant as well as of mycelium in submerged cultures could be observed and total alkaloid yields are rather influenced.