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Production of thermozymocidin (myriocin) by the pyrenomycete Melanconis flavovirens
Author(s) -
Šašek Václav,
Sailer Miroslav,
Vokoun Jindřich,
Musílek Vladimír
Publication year - 1989
Publication title -
journal of basic microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.58
H-Index - 54
eISSN - 1521-4028
pISSN - 0233-111X
DOI - 10.1002/jobm.3620290619
Subject(s) - antifungal , antibiotics , microbiology and biotechnology , chemistry , biology
Submerged culture of the pyrenomycete Melanconis flavovirens produces a strongly active antifungal antibiotic. The antibiotic was isolated from the culture mash. In purified compound the physico‐chemical characteristics, including 1 H NMR spectrum, were estimated. The antibiotic was found to be identical with thermozymocidin (myriocin) as confirmed by comparison with synthetically prepared thermozymocidin.