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Occurrence of squalene and dehydrosqualene in streptomycetes
Author(s) -
Gräfe U.,
Reinhardt G.,
Hänel F.,
Schade W.,
Gumpert J.
Publication year - 1985
Publication title -
journal of basic microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.58
H-Index - 54
eISSN - 1521-4028
pISSN - 0233-111X
DOI - 10.1002/jobm.3620250809
Subject(s) - squalene , chemistry , fraction (chemistry) , biochemistry , terpenoid , streptomyces hygroscopicus , labelling , chromatography , biology , bacteria , streptomyces , genetics
Squalene, dehydrosqualene and related hydrocarbons were found to constitute an essential part of the neutral lipid fraction extracted from mycelia and membranes of S. hygroscopicus, S. griseus and S. noursei. In comparison with the fraction of the triglycerides, these terpenoid compounds failed to incorporate (U‐ 14 C)‐acetic acid throughout pulse labelling experiments. This suggested that the pertinent precursors were formed via alternative routes, for instance by catabolising branched‐chain amino acids.