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Extended spectrum β‐lactamase producing Escherichia coli and Klebsiella pneumoniae : critical tools for antibiotic resistance pattern
Author(s) -
Padmini Nagarajan,
Ajilda Antony Alex Kennedy,
Sivakumar Natesan,
Selvakumar Gopal
Publication year - 2017
Publication title -
journal of basic microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.58
H-Index - 54
eISSN - 1521-4028
pISSN - 0233-111X
DOI - 10.1002/jobm.201700008
Subject(s) - klebsiella pneumoniae , microbiology and biotechnology , escherichia coli , antibiotic resistance , antibiotics , enterobacteriaceae , biology , genetics , gene
Drug resistance is a phenomenon where by an organism becomes fully or partially resistant to drugs or antibiotics being used against it. Antibiotic resistance poses an exacting intimidation for people with underlying medical immune conditions or weakened immune systems. Infections caused by the enzyme extended spectrum β‐lactamase (ESBL) producing multi drug resistance (MDR) Enterobacteriaceae especially Escherichia coli and Klebsiella pneumonia e are resistant to a broad range of beta lactams, including third generation cephalosporins. Among all the pathogens, these two MDR E. coli and K. pneumoniae have emerged as one of the world's greatest health threats in past two decades. The nosocomial infections caused by these ESBL producing MDR E. coli and K. pneumoniae complicated the therapy and limit treatment options.