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Effect of coating the wells of a polystyrene microtiter plate with xanthorrhizol on the biofilm formation of Streptococcus mutans
Author(s) -
Rukayadi Yaya,
Hwang JaeKwan
Publication year - 2006
Publication title -
journal of basic microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.58
H-Index - 54
eISSN - 1521-4028
pISSN - 0233-111X
DOI - 10.1002/jobm.200510088
Subject(s) - biofilm , streptococcus mutans , microtiter plate , polystyrene , chemistry , microbiology and biotechnology , bacteria , dental plaque , chromatography , biology , organic chemistry , polymer , genetics
Colonization on the surface of tooth by Streptococcus mutans is an important step in the initiation of dental plaque. Polystyrene microtiter plates have been employed to study bacterial colonization and biofilm formation of periodontal bacteria. The objective of this work was to evaluate the effect of coating the wells of a polystyrene microtiter plate with xanthorrhizol isolated from java turmeric ( Curcuma xanthorrhiza Roxb .) on Strep. mutans biofilm formation. Our studies demonstrated that coating of a polystyrene microtiter plate with 5 µg/ml of xanthorrhizol resulted in significant (up to 60%) reduction of adherent cells compared to that of cells in uncoated wells. This result suggests that xanthorrhizol displays potent activity in preventing Strep. mutans biofilm formation. (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)