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Leukaemomycin‐geblockte Mutanten des Streptomyces griseus und ihre Pigmente II. Neue 7‐Hydroxy‐bisanhydro‐rhodomycinone aus der Mutante ZIMET 41707/1P
Author(s) -
Ihn W.,
Wagner C.,
Fleck W. F.,
Tresselt D.,
Eritt I.,
Sedmera P.
Publication year - 1984
Publication title -
zeitschrift für allgemeine mikrobiologie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.58
H-Index - 54
eISSN - 1521-4028
pISSN - 0044-2208
DOI - 10.1002/jobm.19840240805
Subject(s) - streptomyces griseus , pigment , chemistry , mutant , streptomyces , microbiology and biotechnology , biochemistry , stereochemistry , biology , genetics , bacteria , organic chemistry , gene
Various blocked mutants were isolated from three leukaemomycin‐(daunomycin‐)producing strains IMET JA 3933, IMET JA 5142 and IMET JA 5570 of Streptomyces griseus by NTG and UV treatments. Among them, one class of four mutants ZIMET 43707/1P, IMET JA 5570/3P, IMET JA 5570/10P and IMET JA 5142/01P1 produced new blue and red pigments. Two red compounds designated 1PI and 1PII are the main components of the pigment complex produced by culture of the blocked mutant ZIMET 43707/1P. This paper describes the isolation of 1PI and IPII; furthermore, the spectral and physicochemical properties of these anthracyclinones and the elucidation of their structures are reported.