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Use of D‐glucosamine and 2‐deoxyglucose in the selective isolation of mutants of the yeast Lipomyces starkeyi derepressed for the production of extracellular endodextranase
Author(s) -
Laires A.,
SpencerMartins I.,
van Uden N.
Publication year - 1983
Publication title -
zeitschrift für allgemeine mikrobiologie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.58
H-Index - 54
eISSN - 1521-4028
pISSN - 0044-2208
DOI - 10.1002/jobm.19830230918
Subject(s) - deoxyglucose , yeast , glucosamine , mutant , chemistry , extracellular , biochemistry , d glucosamine , gene
The glucose analogues 2‐deoxyglucose and D‐glucosamine repressed the production of extracellular endodextranase in the yeast Lipomyces starkeyi. Though both analogues were successfully used for the selective isolation of derepressed and hyperproductive mutants, 2‐deoxyglucose proved to be superior to D‐glucosamine with respect to effective concentration and the avoidance of background growth.