Premium
Enzym‐Induktion in der Hefe Lodderomyces in Gegenwart von n ‐Alkanen
Author(s) -
Müller H.G.,
Mauersberger S.,
Schunck W.H.,
Wiedmann B.
Publication year - 1983
Publication title -
zeitschrift für allgemeine mikrobiologie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.58
H-Index - 54
eISSN - 1521-4028
pISSN - 0044-2208
DOI - 10.1002/jobm.19830230913
Subject(s) - chemistry , cycloheximide , cytochrome , cytochrome c oxidase , biochemistry , yeast , cytochrome p450 reductase , enzyme , cytochrome c , stereochemistry , coenzyme q – cytochrome c reductase , mitochondrion , protein biosynthesis
The utilization of n ‐alkanes is connected with extensive modifications of the yeast cell, especially of the cytochrome P‐450‐containing membrane. Beside the cytochrome P‐450 the NADPH cytochrome P‐450 reductase, the cytochrome b 5 , long‐chain alcohol and long‐chain aldehyde dehydrogenases are induced. The activity of the alkane‐hydroxylating enzyme system grows more than the concentration of its terminal oxidase. The induction of the cytochrome P‐450 is inhibited by cycloheximide. A low concentration of oxygen in the culture medium amplifies the induction both of the alkane‐hydroxylating enzyme system and of catalase and cytochrome oxidase, which are localized in the peroxisomes and mitochondria, respectively.