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Zellteilung und Makromolekülsynthesen in auswachsenden Sporen einer temperatursensitiven filamentösen Mutante von Bacillus subtilis
Author(s) -
Prösch S.,
Hecker M.,
Mach H.,
Mach F.
Publication year - 1982
Publication title -
zeitschrift für allgemeine mikrobiologie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.58
H-Index - 54
eISSN - 1521-4028
pISSN - 0044-2208
DOI - 10.1002/jobm.19820221005
Subject(s) - bacillus subtilis , protein filament , mutant , biology , microbiology and biotechnology , strain (injury) , bacillales , biophysics , chemistry , bacteria , biochemistry , anatomy , genetics , gene
A temperature sensitive mutant of Bacillus subtilis SB 19, strain ts 33‐6 was characterized. This strain grows at 46°C (restrictive temperature) with reduced intensity without septation processes. Under restrictive conditions DNA‐ and RNA‐synthesis are remarkably reduced. DNA, however, is synthesized continuously under restrictive conditions causing the formation of multinuclear filaments. Septation, induced at permissive temperature, is not prevented under restrictive conditions. That means that under restrictive conditions initiation of septation is blocked whereas formation of septa can be observed. Shift‐up experiments have shown that the initiation of septation processes occurs at an early stage of cell cycle.