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Virus‐like particles in yeast: Isolation and infectivity
Author(s) -
Nesterova G. F.,
Kärner J.,
Soom Yo.,
Kozlova T. M.
Publication year - 1978
Publication title -
zeitschrift für allgemeine mikrobiologie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.58
H-Index - 54
eISSN - 1521-4028
pISSN - 0044-2208
DOI - 10.1002/jobm.19780180308
Subject(s) - infectivity , yeast , saccharomyces cerevisiae , virus , strain (injury) , candida tropicalis , virus like particle , chemistry , biology , virology , microbiology and biotechnology , biochemistry , gene , recombinant dna , anatomy
Virus‐like particles containing electron dense cores are seen in thin sections of intact and degenerated cells of a thermosensitive ( ts ) strain of Candida tropicalis. A particulate fraction not present in wild‐type cells has been isolated from the ts cells disrupted by pressure. The particles are 80‐120 nm in diameter. Empty particles with a central cavity are observed. The method of infecting mating pairs of Saccharomyces cerevisiae by partially purified particles is described.

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