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Physiologie und Biochemie der Streptomyceten XI. Unterschiedlicher Einbau von D‐Glucose‐u‐ 14 C in die Paromomycin‐Isomere und in die Bausteine von Paromomycin I
Author(s) -
Köster H.,
Liebermann B.,
Reuter G.
Publication year - 1977
Publication title -
zeitschrift für allgemeine mikrobiologie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.58
H-Index - 54
eISSN - 1521-4028
pISSN - 0044-2208
DOI - 10.1002/jobm.19770170604
Subject(s) - paromomycin , chemistry , glucosamine , biochemistry , antibiotics , aminoglycoside
During application of D‐glucose‐u‐ 14 C paromomycine II is higher labelled and shows a different dependence on the application time than paromomycine I, which is isomer at the paromose part For the two paromose isomeres different rates of synthesis are supposed that change nonproportionally to each other. The distribution of radioactivity in paromomycine I shows that there is no fragmentation of the glucose chain during the biosynthesis of glucosamine, ribose, and paromose I. As to the 2‐deoxystreptamine the result has not been ascertained.