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Physiologie und Biochemie der Streptomyceten X. Biologischer Abbau des Paromomycins und Aktivität der alkalischen Phosphatase in Abhängigkeit von der Antibioticumbildung bei Streptomyces albus var. metamycinus nov. var.
Author(s) -
Liebermann B.,
Köster H.,
Reuter G.
Publication year - 1977
Publication title -
zeitschrift für allgemeine mikrobiologie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.58
H-Index - 54
eISSN - 1521-4028
pISSN - 0044-2208
DOI - 10.1002/jobm.19770170504
Subject(s) - streptomyces albus , biosynthesis , chemistry , mycelium , paromomycin , fermentation , antibiotics , biochemistry , biology , bacteria , enzyme , streptomyces , botany , aminoglycoside , genetics
After adding 14 C‐paromomycin to the fermentation broth we observed a varying course of decomposition of the antibiotic, which is dependent on the intensity of paromomycin biosynthesis running simultaneously At a reduced rate of antibiotic biosynthesis, the activity of alkaline phosphatase is lower than with an increased rate of production. This applies for mycelium as well as for broth.