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Bistabilität in der Aktivität der Glutaminsynthetase bei ammoniumlimitierten Chemostatenkulturen von Escherichia coli ML 30
Author(s) -
Müller P. J.,
Ivanova I. I.,
Bergter F.
Publication year - 1977
Publication title -
zeitschrift für allgemeine mikrobiologie
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.58
H-Index - 54
eISSN - 1521-4028
pISSN - 0044-2208
DOI - 10.1002/jobm.19770170307
Subject(s) - ammonia , ammonium , chemistry , glutamine synthetase , escherichia coli , glutamine , biochemistry , amino acid , organic chemistry , gene
The approximative estimation of the function μ([NH + 4 ]) in cultures of E. coli ML 30 had shown that bistability of the ammonium concentration in ammonium limited continuous cultures could be possible (BERGTER et al. 1977). This phenomenon suggested a bistability in the regulation of ammonia assimilation. Therefore, the activity of one key enzyme of the two ammonia assimilation systems was measured. The distribution of the activity of glutamine synthetase in ammonia limited continuous cultures after different transition states confirmed this suggestion.