Postnatal decrease of acetate concentration in rat cerebellum | Zendy

Martin M. | Zendy; Merele M. | Zendy; Labouesse J. | Zendy; Canioni P. | Zendy

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Postnatal decrease of acetate concentration in rat cerebellum

Author(s) -

Martin M.,

Merele M.,

Labouesse J.,

Canioni P.

Publication year - 1994

Publication title -

journal of neuroscience research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.72

H-Index - 160

eISSN - 1097-4547

pISSN - 0360-4012

DOI - 10.1002/jnr.490370114

Subject(s) - cerebellum , glutamate receptor , period (music) , medicine , endocrinology , biology , chemistry , neuroscience , biochemistry , receptor , physics , acoustics

We examined the evolution of 1 H‐NMR detectable metabolites in rat cerebellum fro the postnatal day 1–25, a period associated with intense metabolic changes as well as physiological and morphological modifications. The unexpected result reported here is the existence of a high concentration of acetate in neonatal rat cerebellum, progressively decreasing with age and maturation. In contrast, the cerebellum content of various metabolites such as N ‐acetyl‐ L ‐as‐partate (NAA), glutamate, and aspartate increases from the first day onward. © 1994 Wiley‐Liss, Inc.

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