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Postnatal decrease of acetate concentration in rat cerebellum
Author(s) -
Martin M.,
Merele M.,
Labouesse J.,
Canioni P.
Publication year - 1994
Publication title -
journal of neuroscience research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.72
H-Index - 160
eISSN - 1097-4547
pISSN - 0360-4012
DOI - 10.1002/jnr.490370114
Subject(s) - cerebellum , glutamate receptor , period (music) , medicine , endocrinology , biology , chemistry , neuroscience , biochemistry , receptor , physics , acoustics
We examined the evolution of 1 H‐NMR detectable metabolites in rat cerebellum fro the postnatal day 1–25, a period associated with intense metabolic changes as well as physiological and morphological modifications. The unexpected result reported here is the existence of a high concentration of acetate in neonatal rat cerebellum, progressively decreasing with age and maturation. In contrast, the cerebellum content of various metabolites such as N ‐acetyl‐ L ‐as‐partate (NAA), glutamate, and aspartate increases from the first day onward. © 1994 Wiley‐Liss, Inc.