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Effect of dexamethasone on the nerve growth factor‐induced increase in the NILE glycoprotein in PC12 cells
Author(s) -
Tocco M. D.,
Fujita K.,
Guroff G.
Publication year - 1992
Publication title -
journal of neuroscience research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.72
H-Index - 160
eISSN - 1097-4547
pISSN - 0360-4012
DOI - 10.1002/jnr.490310105
Subject(s) - nerve growth factor , dexamethasone , glycoprotein , nile red , nerve cells , p glycoprotein , microbiology and biotechnology , medicine , chemistry , endocrinology , biology , biochemistry , physics , receptor , antibiotics , multiple drug resistance , quantum mechanics , fluorescence
The long‐known and well‐documented increase in the NILE glycoprotein produced by nerve growth factor in PC12 cells is prevented by simultaneous treatment with dexamethasone. The absence of this surface marker on the fully differentiated cells has been demonstrated by both glucosamine incorporation and immunohistofluorescence.