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Effect of gender on glucose utilization rates in healthy humans: A positron emission tomography study
Author(s) -
Miura S. A.,
Schapiro M. B.,
Grady C. L.,
Kumar A.,
Salerno J. A.,
Kozachuk W. E.,
Wagner E.,
Rapoport S. I.,
Horwitz B.
Publication year - 1990
Publication title -
journal of neuroscience research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.72
H-Index - 160
eISSN - 1097-4547
pISSN - 0360-4012
DOI - 10.1002/jnr.490270410
Subject(s) - positron emission tomography , nuclear medicine , medicine , positron , brain positron emission tomography , psychology , preclinical imaging , in vivo , biology , physics , quantum mechanics , electron , microbiology and biotechnology
Positron emission tomography (PET) was used with 18 fluorodeoxyglucose to see if gender differences in resting cerebral glucose utilization could be detected. Thirty‐two healthy subjects (15 women and 17 men; age range: 21–38 yr) were examined using a high‐resolution PET scanner to determine the regional cerebral metabolic rate for glucose (CMRglc) in 65 gray matter regions of interest. Whole brain CMRglc did not differ significantly between the two genders, nor did any of the regional CMRglc values. Only 1 of 65 ratios of regional‐to‐whole brain CMRglc differed significantly between men and women, which is consistent with chance. These results indicate that there are no differences in resting regional cerebral glucose utilization between young men and women.