The site of the integration of muscular activity and respiration

Acutely decerebrate (midcollicular) cats do not, or rarely if ever, walk spontaneously; nor do they show phasic movements of progression. After low thoracic cordotomy in a Schiff‐Sherrington preparation with enhanced forelimb rigidity, appproximately 50% of the preparations begin to show spontaneous locomotory movements in the forelimbs. In some cases these movements are in periodic bursts, and at these times are associated with waxing hyperpnea beginning before the onset of the forelimb movements. This indicates the presence of an intrinsic exercise hyperpnea mechanism mediated within the central nervous system in centers caudal to the hypothalamus.