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Long‐term effect of electroshock treatment on the entry of calcium into the cerebroventricular fluid in the rat
Author(s) -
Barkai Amiram I.
Publication year - 1983
Publication title -
journal of neuroscience research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.72
H-Index - 160
eISSN - 1097-4547
pISSN - 0360-4012
DOI - 10.1002/jnr.490090208
Subject(s) - term (time) , calcium , medicine , convulsive therapy , neuroscience , psychology , physics , electroconvulsive therapy , electroconvulsive shock , quantum mechanics
The rate of appearance (R a ) of calcium (Ca) in the cerebroventricular compartment of urethane‐anesthesized rats was determined by two methods: one is measurement of isotope dilution during ventricular‐cisternal perfusion with artificial cerebrospinal fluid (CSF) containing 45 Ca, the other is estimation of the rate of entry of 45 Ca from plasma after rapid injection of tracer 45 CaCl 2 intravenously. Electroshock treatment (EST) for 3 successive days resulted in a marked increase in the rate of entry of calcium from blood to CSF. The effect of EST on the permeability of the blood‐CSF bamer to Ca could be observed even 24 hr after the generalized seizure induced by electroshock has terminated.