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Failure of nerve growth factor to enhance wound healing in the hamster
Author(s) -
Leitzel Kim,
Cano Cheryl,
Marks James,
Lipton Allan
Publication year - 1982
Publication title -
journal of neuroscience research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.72
H-Index - 160
eISSN - 1097-4547
pISSN - 0360-4012
DOI - 10.1002/jnr.490080228
Subject(s) - nerve growth factor , hamster , wound healing , growth factor , medicine , pharmacology , endocrinology , surgery , receptor
We have investigated the effect of topically applied high molecular weight nerve growth factor (HMW‐NGF) and 7S nerve growth factor (7S NGF) on healing of full‐thickness skin wounds in the Syrian hamster. Our results indicate that HMW‐NGF and 7S NGF have no significant influence on the rate of wound contraction or on the time to complete healing in this animal model.