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Choline acetyltransferase: Purification and characterization
Author(s) -
Chao LiPen
Publication year - 1980
Publication title -
journal of neuroscience research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.72
H-Index - 160
eISSN - 1097-4547
pISSN - 0360-4012
DOI - 10.1002/jnr.490050202
Subject(s) - choline acetyltransferase , acetylcholine , choline , cholinergic , enzyme , neurotransmitter , biochemistry , chemistry , biology , neuroscience , pharmacology , receptor
Choline acetyltransferase catalyzes the synthesis of the neurotransmitter acetylcholine and is the specific enzyme marker for cholinergic neurons. This review summarizes and discusses different purification procedures, as well as the characteristics of this important enzyme. Explanations for conflicting or controversial results concerning this enzyme are also discussed.