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Cannabis sativa: Ultrastructural changes in organelles of neurons in brain septal region of monkeys
Author(s) -
Myers William A.,
Heath Robert G.
Publication year - 1979
Publication title -
journal of neuroscience research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.72
H-Index - 160
eISSN - 1097-4547
pISSN - 0360-4012
DOI - 10.1002/jnr.490040103
Subject(s) - endoplasmic reticulum , ultrastructure , golgi apparatus , organelle , fragmentation (computing) , mitochondrion , biology , cannabis sativa , chemistry , anatomy , neuroscience , microbiology and biotechnology , botany , ecology
Abstract Ultrastructural studies of layer V pyramidal neurons of the septal region of rhesus monkeys exposed to smoke of active marihuana and of those exposed to intravenous delta‐9‐THC revealed low volume density and various degrees of fragmentation and disorganization of rough endo‐plasmic reticulum. In contrast, no changes were observed in these neurons of the septal region of control monkeys (unexposed monkeys and one monkey exposed to smoke of inactive marihuana). There were no significant differences in volume density of mitochondria or golgi apparatus between exposed animals and controls.