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In vitro vs in situ development of Purkinje cells
Author(s) -
PalaciosPrü Ernesto,
Palacios Laura,
Mendoza Rosa V.
Publication year - 1976
Publication title -
journal of neuroscience research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.72
H-Index - 160
eISSN - 1097-4547
pISSN - 0360-4012
DOI - 10.1002/jnr.490020503
Subject(s) - in vitro , in situ , biology , microbiology and biotechnology , embryo , cellular differentiation , neuroscience , chemistry , biochemistry , organic chemistry , gene
Abstract Analysis of in vitro vs in situ development of Purkinje cells was undertaken in order to compare the transitory morphology of Purkinje cells grown in situ with their differentiation in vitro. Purkinje cells in rotary cultures developed their basic morphological pattern only when the cultures were prepared from 16‐day chick embryos, indicating the existence of a critical period during their normal differentiation, which lasted approximately 24 hr between days 14 and 15 of embryonic development.