Pattern of labeling of poly (A)‐associated RNA in the CA 3  region of rat hippocampus during training | Zendy

Cupello Aroldo | Zendy; Hydén Holger | Zendy

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Pattern of labeling of poly (A)‐associated RNA in the CA 3 region of rat hippocampus during training

Author(s) -

Cupello Aroldo,

Hydén Holger

Publication year - 1976

Publication title -

journal of neuroscience research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.72

H-Index - 160

eISSN - 1097-4547

pISSN - 0360-4012

DOI - 10.1002/jnr.490020402

Subject(s) - hippocampal formation , messenger rna , hippocampus , nerve cells , neuroscience , rna , biology , microbiology and biotechnology , chemistry , endocrinology , anatomy , medicine , biochemistry , gene

Newly synthesized poly (A)‐associated mRNA was analysed in the hippocampal CA 3 pyramidal nerve cells in rats subjected to training to reverse handedness. The nerve cells of trained animals showed a smaller percentage of poly (A)‐associated mRNA than did the active controls. However, a specific fraction of this poly (A) hippocampal RANA with a S E value of around 25 was reproducibly stimulated. This qualitative nerve cell mRNA change is discussed in relation to similar changes in the protein pattern as a function of training.

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