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Neurochemical changes in the cat's spinal cord due to orthodromic tetanic stimuli. I: Phospholipids
Author(s) -
Althasu H. H.,
Neuhoff V.,
Haase J.,
Ross H.G.
Publication year - 1975
Publication title -
journal of neuroscience research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.72
H-Index - 160
eISSN - 1097-4547
pISSN - 0360-4012
DOI - 10.1002/jnr.490010306
Subject(s) - orthodromic , neurochemical , neuroscience , spinal cord , tetanic stimulation , medicine , chemistry , psychology , stimulation , inhibitory postsynaptic potential , excitatory postsynaptic potential
Posttetanic potentiation of monosynaptic reflexes has been used as a paradigm for neuronal plasticity. The explanation for this phenomenon is an increased responsiveness of the synaptic junctions. This would basically required chemical changes of the nervous structures involved. The ventral horn area of the spinal cord was therefore analyzed neurochemically. The determination of the phospholipids revealed an alteration of their composition. Sphingomyelin, phosphatidylcholine and phosphatidylinositide/serine behaved differently, whereas phosphatidylethanolamine and the total phospholipid content remained unchanged.