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Neural correlates of visuoperceptive changes in severe alcohol use disorder: A critical review of neuroimaging and electrophysiological findings
Author(s) -
Creupelandt Coralie,
D'Hondt Fabien,
Maurage Pierre
Publication year - 2021
Publication title -
journal of neuroscience research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.72
H-Index - 160
eISSN - 1097-4547
pISSN - 0360-4012
DOI - 10.1002/jnr.24799
Subject(s) - neuroimaging , neural correlates of consciousness , psychology , functional neuroimaging , neuroscience , alcohol use disorder , alcohol , cognition , biology , biochemistry
Visuoperceptive deficits are frequently reported in severe alcohol use disorder (SAUD) and are considered as pervasive and persistent in time. While this topic of investigation has previously driven researchers' interest, far fewer studies have focused on visuoperception in SAUD since the ‘90s, leaving open central questions regarding the origin and implications of these deficits. To renew research in the field and provide a solid background to work upon, this paper reviews the neural correlates of visuoperception in SAUD, based on data from neuroimaging and electrophysiological studies. Results reveal structural and functional changes within the visual system but also in the connections between occipital and frontal areas. We highlight the lack of integration of these findings in the dominant models of vision which stress the dynamic nature of the visual system and consider the presence of both bottom‐up and top‐down cerebral mechanisms. Visuoperceptive changes are also discussed in the framework of long‐lasting debates regarding the influence of demographic and alcohol‐related factors, together stressing the presence of inter‐individual differences. Capitalizing on this review, we provide guidelines to inform future research, and ultimately improve clinical care.