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The myelinated axon is dependent on the myelinating cell for support and maintenance: Molecules involved
Author(s) -
Edgar J.M.,
Garbern J.
Publication year - 2004
Publication title -
journal of neuroscience research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.72
H-Index - 160
eISSN - 1097-4547
pISSN - 0360-4012
DOI - 10.1002/jnr.20063
Subject(s) - axon , myelin , neuroscience , schwann cell , myelin sheath , microbiology and biotechnology , biology , chemistry , central nervous system
The myelin‐forming cells, oligodendrocytes and Schwann cells, extend processes that spirally wrap axons and provide the insulation that allows rapid saltatory conduction. Recent data suggest a further role for the myelin‐forming cells in axonal support and maintenance. This Mini‐Review summarises some of the data that support this view and highlights the molecules involved. © 2004 Wiley‐Liss, Inc.