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The breadth of concomitant virological features in a family cluster outbreak of COVID‐19 pneumonia
Author(s) -
Lei Guanglin,
Meng Fanping,
Wang Cheng,
Yan Jin,
Sun Fang,
Shi Lei,
Li Wengang,
Luan Junqing,
Wang Siyu,
Yang Penghui
Publication year - 2021
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.27055
Subject(s) - outbreak , concomitant , virology , coronavirus , pneumonia , feces , virus , atypical pneumonia , titer , viral shedding , covid-19 , cluster (spacecraft) , viral pneumonia , biology , immunology , medicine , disease , infectious disease (medical specialty) , microbiology and biotechnology , programming language , computer science
An outbreak of a novel coronavirus disease (COVID‐19) caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) had emerged in 2019 and rapidly posed a global epidemic. Here, we report the breadth of concomitant virological features of a family cluster with COVID‐19. The period of virus shedding is significantly different between upper respiratory and feces samples. Even the SARS‐CoV‐2 virus titers were undetectable in feces, it could be positive again soon and likely related to fluctuated inflammation levels (interleukin‐6, etc.) and lowered immune responses (CD4 + T lymphocyte, etc.). Our findings expand the novel understanding of the breadth of concomitant virological features during a non‐severe family cluster of COVID‐19.