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A meta‐analysis of human papillomavirus prevalence and types among Iranian women with normal cervical cytology, premalignant lesions, and cervical cancer
Author(s) -
Salavatiha Zahra,
Farahmand Mohammad,
Shoja Zabihollah,
Jalilvand Somayeh
Publication year - 2021
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.26928
Subject(s) - medicine , cervical cancer , cytology , human papillomavirus , cervix , cervical intraepithelial neoplasia , atypia , gynecology , koilocyte , hpv infection , cancer , pathology
Abstract In this study, all data from Iran on human papillomavirus (HPV) prevalence and types among women with normal cervical cytology, premalignant lesions, and cervical cancer were obtained and pooled. The overall HPV prevalence was found to be 9% in women with a normal cervix, 55% in atypical squamous cells of undetermined significance or atypia cases, 58% and 69% in women with low and high grade squamous intraepithelial lesions, respectively, and 81% among women with invasive cervical cancer. In all of the studied groups, HPV 16 was the most common HPV type, followed by HPV 18. In conclusion, this meta‐analysis revealed that it will be beneficial if current HPV vaccines are integrated into the national vaccination programs of Iran.

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