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Hepatitis C virus genotypes in hemodialysis patients in Angola
Author(s) -
da Costa Marques Borges Luis Filipe,
Zalis Mariano Gustavo,
SantoroLopes Guilherme,
Varella Rafael Brandão
Publication year - 2019
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.25354
Subject(s) - genotype , virology , genotyping , viremia , hepatitis c virus , flaviviridae , hepacivirus , hepatitis c , hemodialysis , medicine , virus , biology , genetics , gene
To our knowledge, there are no published data on hepatitis C virus (HCV) genotypes in Angola. This study aimed at assessing the distribution of HCV genotypes in seropositive hemodialysis patients in Luanda. Among 51 HCV‐positive subjects included, viremia was detected in 27 (53%). HCV genotyping was performed by bidirectional sequencing of the 5'‐untranslated region by the Sanger method. HCV genotype 4 was largely predominant (20 cases; 74%), followed by genotypes 1b (5 cases; 18.5%), 1a and 2 (one case each; 3.7%). These results suggest that the distribution of HCV genotypes in Angola is similar to that reported from other Central African countries.