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Intravaginal practices and genital human papillomavirus infection among female sex workers in Cambodia
Author(s) -
Bui Thanh Cong,
Scheurer Michael E.,
Pham Vy ThiTuong,
Tran Ly ThiHai,
Hor Leng Bun,
Vidrine Damon J.,
Ross Michael W.,
Markham Christine M.
Publication year - 2018
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.25268
Subject(s) - vagina , human papillomavirus , sex organ , medicine , gynecology , poisson regression , hpv infection , confidence interval , intravaginal administration , female sex , obstetrics , demography , biology , environmental health , surgery , population , cervical cancer , genetics , cancer , sociology
Objectives Intravaginal practices (IVPs) include washing, wiping, or inserting something inside the vagina. This study investigates the associations between IVPs and genital human papillomavirus (HPV) infection. Methods We conducted a cross‐sectional study of 200 female sex workers aged 18 to 35 years in Phnom Penh, Cambodia. From August to September 2014. Data on sociodemographic characteristics, IVPs, and other behaviors were collected through face‐to‐face interviews. Self‐collected cervicovaginal specimens were tested for 37 HPV genotypes. Results Multivariable Poisson regression models showed that a lower number of infecting HPV genotypes were associated with intravaginal washing in the past 3 months (incident rate ratios [IRR] = 0.65, 95% confidence interval [CI]: 0.46‐0.94) and often performing intravaginal washing shortly after sex (IRR = 0.89, 95% CI: 0.81–0.99). Intravaginal washing before vaginal sex, intravaginal wiping, and intravaginal insertion were not associated with HPV infection. Conclusion These findings challenge the existing view that all types of vaginal cleansing are harmful. Specifically, intravaginal washing shortly after sex (mainly with water) may help prevent HPV infection in female sex workers, who have several partners and thus frequently expose to sources of HPV infection with different genotypes.