Premium
Prevalence of C‐C chemokine receptor type 5 tropism among human immunodeficiency virus 1–infected patients in South Korea
Author(s) -
Song Je Eun,
Ahn Mi Young,
Kim Woo Joo,
Kim ShinWoo,
Lee Jin Soo,
Ku Nam Su,
Kim Joon Hyung,
Kim KiHyon,
Ann Heawon,
Choi Jun Yong
Publication year - 2018
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.25254
Subject(s) - tropism , virology , tissue tropism , maraviroc , ccr5 receptor antagonist , biology , genotype , chemokine receptor , virus , cxcr4 , population , chemokine , medicine , human immunodeficiency virus (hiv) , receptor , genetics , gene , environmental health
The discovery of two main coreceptors for human immunodeficiency virus (HIV), C-C chemokine receptor type 5 (CCR5), and C-X-C chemokine receptor type 4 has led to a better understanding of the interaction between HIV envelope and host cells, and development of new therapeutic approaches. The purpose of this study was to estimate the prevalence of CCR5 tropism among HIV-1-infected Koreans and identify the predictors for CCR5 tropism.