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Presence of rare hepatitis C virus subtypes, 2j, 2k, and 2r in Mexico City as identified by sequencing
Author(s) -
UribeNoguez Luis Antonio,
OcañaMondragón Alicia,
MataMarín José Antonio,
GómezTorres María Elena,
RibasAparicio Rosa María,
MartínezRodríguez María
Publication year - 2018
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.25070
Subject(s) - virology , ns5b , hepatitis c virus , genotype , virus , hepacivirus , hepatitis c , medicine , biology , genetics , gene
The HCV 5'UTR, Core/E1, and NS5B regions of samples from fifty patients infected with the hepatitis C virus (HCV) were analyzed. Seventeen patients were identified with genotype (GT) 1b, eleven with GT‐1a, nine with GT‐2b and four with GT‐3a. Two rare subtypes were detected: GT‐2j in two patients and GT‐2r in one patient. Three patients had mixed infections: one with GT‐2k + 2j and two with GT‐1b + 2b. This work identifies HCV GTs, 2j, 2k, and 2r for the first time in Mexico.