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An evaluation of asymptomatic Dengue infections among blood donors during the 2014 Dengue outbreak in Guangzhou, China
Author(s) -
Liao Qiao,
Shan Zhengang,
Wang Min,
Huang Jieting,
Xu Ru,
Huang Ke,
Tang Xi,
Zhang Weiyun,
Nelson Kenrad,
Li Chengyao,
Fu Yongshui,
Rong Xia
Publication year - 2017
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.24883
Subject(s) - dengue fever , outbreak , dengue virus , virology , asymptomatic , antibody , medicine , immunology , biology
In 2014, an outbreak of dengue virus (DENV) infection led to 45 171 clinical cases diagnosed in Guangdong province, Southern China. However, the potential risk of blood donors asymptomatically infected with DENV has not been evaluated . In the current study we detected anti‐DENV IgG antibody and RNA in volunteer Chinese blood donors. We found that anti‐DENV IgG antibody was positively detected in 3.4% (51/1500) and two donors were detected as being DENV RNA positive out of 3000 blood samples. We concluded that the presence of potential DENV in blood donors might be potential risk for blood safety. Therefore, screening for DENV infection should be considered in blood donations during a period of dengue outbreak in high epidemic area of China.

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