Premium
Low prevalence of IgG antibodies against antigens of HEV genotypes 1 and 3 in women with a high‐risk pregnancy
Author(s) -
BaptistaGonzález Héctor,
TruebaGómez Rocío,
RosenfeldMann Fanny,
RoqueÁlvarez Elsa,
MéndezSánchez Nahúm
Publication year - 2017
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.24878
Subject(s) - medicine , asymptomatic , pregnancy , antibody , genotype , immunology , virology , biology , biochemistry , genetics , gene
The aim of the study was to assess whether high‐risk pregnant women have a higher prevalence of HEV during the perinatal period. This was a cross‐sectional study of 428 patients: Group 1, 127 women with a high‐risk pregnancy; Group 2, 97 asymptomatic people with reactivity to HCV or HBV; Group 3, 94 patients with clinical symptoms suggestive of HEV infection; and Group 4, 110 healthy blood donors from an urban area of Mexico City. ELISA was used to measure antibody to HEV genotypes 1 and 3. The prevalence rates of anti‐HEV IgG antibodies were 0.79% in Group 1, 2.1% in Group 2, 7.4% in Group 3, and 0% in Group 4. Women with a high‐risk pregnancy did not have a higher prevalence of HEV infection in this clinical setting.