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The use of human sewage screening for community surveillance of hepatitis E virus in the UK
Author(s) -
Smith Donald B.,
Paddy Julius O.,
Simmonds Peter
Publication year - 2016
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.24403
Subject(s) - hepatitis e virus , virology , virus , hepatitis e , limiting , biology , amplicon , medicine , viral disease , genotype , polymerase chain reaction , gene , genetics , mechanical engineering , engineering
Hepatitis E virus sequences were detected by RT‐PCR in 14/15 (93%) of untreated sewage samples from Edinburgh, Scotland, UK. Phylogenetic analysis of amplicons at limiting dilution revealed the co‐circulation of multiple variants of HEV‐3, with a pattern of diversity matching that observed in a local cohort of HEV‐infected hepatitis patients. J. Med. Virol. 88:915–918, 2016 . © 2015 The Authors. Journal of Medical Virology Published by Wiley Periodicals, Inc.