The use of human sewage screening for community surveillance of hepatitis E virus in the UK | Zendy

Smith Donald B. | Zendy; Paddy Julius O. | Zendy; Simmonds Peter | Zendy

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The use of human sewage screening for community surveillance of hepatitis E virus in the UK

Author(s) -

Smith Donald B.,

Paddy Julius O.,

Simmonds Peter

Publication year - 2016

Publication title -

journal of medical virology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.782

H-Index - 121

eISSN - 1096-9071

pISSN - 0146-6615

DOI - 10.1002/jmv.24403

Subject(s) - hepatitis e virus , virology , virus , hepatitis e , limiting , biology , amplicon , medicine , viral disease , genotype , polymerase chain reaction , gene , genetics , mechanical engineering , engineering

Hepatitis E virus sequences were detected by RT‐PCR in 14/15 (93%) of untreated sewage samples from Edinburgh, Scotland, UK. Phylogenetic analysis of amplicons at limiting dilution revealed the co‐circulation of multiple variants of HEV‐3, with a pattern of diversity matching that observed in a local cohort of HEV‐infected hepatitis patients. J. Med. Virol. 88:915–918, 2016 . © 2015 The Authors. Journal of Medical Virology Published by Wiley Periodicals, Inc.

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