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Three infants with rotavirus gastroenteritis complicated by severe gastrointestinal bleeding
Author(s) -
Kawamura Yoshiki,
Miura Hiroki,
Mori Yuji,
Sugata Ken,
Nakajima Yoichi,
Yamamoto Yasuto,
Morooka Masashi,
Tsuge Ikuya,
Yoshikawa Akiko,
Taniguchi Koki,
Yoshikawa Tetsushi
Publication year - 2016
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.24297
Subject(s) - melena , rotavirus , gastrointestinal bleeding , medicine , rotavirus gastroenteritis , rotavirus infections , virology , gastroenterology , diarrhea , pediatrics
Rotavirus gastroenteritis causes substantial morbidity and mortality worldwide in children. We report three infants with rotavirus gastroenteritis complicated by various severity of gastrointestinal bleeding. Two patients (cases 1 and 2) recovered completely without any specific treatments. One patient (case 3) died despite extensive treatments including a red blood cell transfusion and endoscopic hemostatic therapy. Rotavirus genotypes G1P[8] and G9P[8] were detected in cases 2 and 3, respectively. Rotavirus antigenemia levels were not high at the onset of melena, suggesting that systemic rotaviral infection does not play an important role in causing melena. J. Med. Virol. 88:171–174, 2016 . © 2015 Wiley Periodicals, Inc.