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The role of rhinovirus in children hospitalized for acute respiratory disease, Santa Fe, Argentina
Author(s) -
Rudi Juan Manuel,
Molina Fabiana,
Díaz Rocío,
Bonet Virginia,
Ortellao Lucila,
Cantarutti Diego,
Gómez Alejandra,
Pierini Judith,
Cociglio Raquel,
Kusznierz Gabriela
Publication year - 2015
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.24266
Subject(s) - bronchiolitis , rhinovirus , pneumonia , medicine , bronchitis , epidemiology , respiratory tract infections , asthma , pediatrics , respiratory system , respiratory disease , chronic bronchitis , lung
Human rhinoviruses (HRVs) were historically considered upper airway pathogens. However, they have recently been proven to cause infections in the lower respiratory tract, resulting in hospitalization of children with pneumonia, bronchiolitis, and chronic pulmonary obstruction. In this report, HRV frequency and seasonality are described together with patient clinical‐epidemiological aspects. From a total of 452 surveyed samples, the HRV nucleic acids was detected in 172 (38.1%) and found in every month of the study year. 60% of inpatients with acute respiratory infection (ARI) associated with HRV were under 6 months of age and 31% had a clinical history, being preterm birth and recurrent wheezing the prevailing conditions. The most frequent discharge diagnoses were pneumonia (35.2%), bronchiolitis (32.4%), and bronchitis (12.4%). Fifteen point nine percent of patients required admission into intensive care units. The results obtained in this study demonstrated the association between HRV and children hospitalizations caused by ARI. J. Med. Virol. 87:2027–2032, 2015 . © 2015 Wiley Periodicals, Inc.