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Polymorphisms in cytomegalovirus genotype in immunocompetent patients with corneal endotheliitis or iridocyclitis
Author(s) -
Oka Naoko,
Suzuki Takashi,
Inoue Tomoyuki,
Kobayashi Takeshi,
Ohashi Yuichi
Publication year - 2015
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.24239
Subject(s) - cytomegalovirus , virology , medicine , ophthalmology , genotype , keratitis , herpesviridae , biology , viral disease , virus , gene , biochemistry
Cytomegalovirus (CMV) that caused corneal endotheliitis and iridocyclitis in immunocompetent patients was genotyped. The gB type1 was detected in seven endotheliitis samples (77.8%) and five iridocyclitis samples (100%), and the gB type 3 was detected in two endotheliitis samples (22.2%). The UL144 type 1 was found in five endotheliitis samples (45.5%) and five iridocyclitis samples (83.3%). The UL144 type 2 was found in two endotheliitis samples (18.2%) and one iridocyclitis sample (16.7%). The gB type 1 was predominant in endotheliitis and iridocyclitis, and the CMV genotypes in eyes with endotheliitis and iridocyclitis were similar. J. Med. Virol. 87:1441–1445, 2015 . © 2015 Wiley Periodicals, Inc.