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Lack of adenovirus DNA in mediastinal adipose tissue of obese/overweight adults with cardiovascular disorders?
Author(s) -
BilLula Iwona,
Płonek Tomasz,
Woźniak Mieczysław
Publication year - 2014
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.23849
Subject(s) - adipose tissue , anterior mediastinum , mediastinum , overweight , pericardium , medicine , obesity , pathology , biology , endocrinology , anatomy
Mediastinal adipose tissue can be found on the anterior surface of pericardial sac below the remnants of the thymus. On the basis of previous studies describing adenoviruses (AdVs) as a causative factor of obesity, the causative relation between the presence of AdVs and an increased accumulation of mediastinal adipose tissue was studied. The study included 25 obese/overweight subjects with cardiac disorders. Specimens from fat deposits from the anterior mediastinum were collected during cardiac surgery procedures. Afterwards, PCR was used to detect AdV‐DNA. No AdV‐DNA could be detected in adipose tissue. An association between an excessive accumulation of mediastinal adipose tissue and an AdV‐infection in the development of accompanying cardiac disorders was excluded. J. Med. Virol. 86:802–805, 2014 . © 2013 Wiley Periodicals, Inc.