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Enteric viral pathogens in children with inflammatory bowel disease
Author(s) -
Kolho KaijaLeena,
Klemola Päivi,
SimonenTikka MarjaLeena,
Ollonen MarjaLiisa,
Roivainen Merja
Publication year - 2012
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.23193
Subject(s) - sapovirus , norovirus , astrovirus , inflammatory bowel disease , rotavirus , medicine , virology , ulcerative colitis , enterovirus , feces , disease , virus , diarrhea , gastroenterology , microbiology and biotechnology , biology
The causes of exacerbations of inflammatory bowel disease (IBD) are unknown. The presence of RNA of an enterovirus, norovirus GI, norovirus GII, rotavirus, astrovirus, and sapovirus was sought in stool samples of 50 children (median age 12.9 years) undergoing gastrointestinal endoscopies for IBD or its exclusion (Crohn's disease n = 18, ulcerative colitis n = 13, indeterminate colitis n = 2, non‐IBD n = 17). Viral RNA was found in three fecal samples (norovirus GII n = 2, sapovirus n = 1), all in children without IBD. Therefore, enteral viruses may play only a minor role in IBD. J. Med. Virol. 84:345–347, 2012. © 2011 Wiley Periodicals, Inc.