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Evolution of Anelloviridae strains distribution in serial blood and biopsy samples from a renal transplant patient
Author(s) -
Biagini Philippe,
Bédarida Sandra,
Dussol Bertrand,
Daniel Laurent,
Berland Yvon,
de Micco Philippe
Publication year - 2012
Publication title -
journal of medical virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.782
H-Index - 121
eISSN - 1096-9071
pISSN - 0146-6615
DOI - 10.1002/jmv.22259
Subject(s) - kidney transplant , renal transplant , biopsy , sequence (biology) , biology , dna , natural history , pathology , kidney transplantation , virology , medicine , kidney , genetics
A few studies investigated the natural history of viruses belonging to the family Anelloviridae in transplant patient. The case of a 64‐year‐old kidney transplant recipient is described. Molecular analysis of serial blood samples collected before and after transplant was performed during a period of 510 days. Two kidney biopsies were also analyzed. All blood samples tested positive for Anelloviridae DNA, with the identification of sequences belonging to the three taxonomic genera identified in humans. Sequences distribution during the follow‐up was multimodal. A sequence nearly identical to one present in the blood before transplant was further characterized in one biopsy sample. J. Med. Virol. 84:96–98, 2011. © 2011 Wiley Periodicals, Inc.